Chemistry of α-mangostin. Studies on the semisynthesis of minor xanthones from Garcinia mangostana
نویسندگان
چکیده
منابع مشابه
Chemistry of α-mangostin. Studies on the semisynthesis of minor xanthones from Garcinia mangostana.
α-Mangostin is the major prenylated xanthone from Garcinia mangostana and it has been used also in recent times as starting material for the semisynthetic preparation of various biologically active derivatives. Its structure is characterised by the presence of few functional groups amenable to chemical manipulations, but present in the molecule in multiple instances (three phenolic hydroxyl gro...
متن کاملPotential Application of Modified α-Mangostin Xanthones from Garcinia mangostana as Antibacterial Agents in Food Packaging
The microbial contamination in food packaging have been a major concern that paved the way for the search for natural based new anti-microbial agents, such as modified α-mangostin. In the present work, twelve synthetic analogs were obtained via semi-synthetic modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C), alkylation, and acetylation. The evaluation of the ...
متن کاملXanthones from the Pericarp of Garcinia mangostana.
Mangosteen (Garcinia mangostana L.) is one of the most popular tropical fruits (called the "Queen of Fruits"), and is a rich source of oxygenated and prenylated xanthone derivatives. In the present work, phytochemical investigation has resulted in one new prenylated xanthone and 13 known xanthones isolated from the pericarp of G. mangostana. Their structures were established by spectroscopic da...
متن کاملXanthones from the heartwood of Garcinia mangostana.
Twelve xanthones were isolated from the hexane extract of the heartwood of Garcinia mangostana from Myanmar. Their structures were determined using 1D and 2D NMR techniques
متن کاملAntileptospiral activity of xanthones from Garcinia mangostana and synergy of gamma-mangostin with penicillin G
BACKGROUND Leptospirosis, one of the most widespread zoonotic infectious diseases worldwide, is caused by spirochetes bacteria of the genus Leptospira. The present study examined inhibitory activity of purified xanthones and crude extracts from Garcinia mangostana against both non-pathogenic and pathogenic leptospira. Synergy between γ-mangostin and penicillin G against leptospires was also det...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Natural Product Research
سال: 2014
ISSN: 1478-6419,1478-6427
DOI: 10.1080/14786419.2014.986729